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The ELAD trial (Evaluating the Effects of the Novel GLP-1 Analogue Liraglutide in Alzheimers Disease) was a Phase 2b randomized, double-blind, placebo-controlled study in ~204 patients with mild AD

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Among these mutations, the G919A transition, leading to substitution of guanine by adenine in position 919, frequently encountered in the Irish population, is observed in subjects who are refractory to vitamin B 6 treatment

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